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Tamsulosin Hydrochloride is primarily used for benign prostatic hyperplasia, but is sometimes used for the passage of kidney stones by the same mechanism of smooth muscle relaxation via alpha antagonism. Benign prostatic hyperplasia (BPH) also known as benign prostatic hypertrophy (technically a misnomer), benign enlargement of the prostate (BEP), and adenofibromyomatous hyperplasia, refers to the increase in size of the prostate in middle-aged and elderly men.
Chemical Name : Tamsulosin Hydrochloride
CAS Number : 106463-17-6
Alternate CAS Number : 106133-20-4 (Free Base)
Synonyms : 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide; Flomax; LY-253352; Tamsulosin; Tamsulosin hydrochloride; YM 617; YM-617.
Molecular Formula : C20H28N2O5S·HCl
Molecular Weight : 444.97 (408.51 +36.46)
Appearance : White to Off-White Crystalline Solid
Melting Point : 227-230°C
Specific Rotation : 18-20.5°
Solubility : Water, Methanol, Acetone(Slightly), DMSO(Slightly)
Category : Pharmaceutical/Standards/API Drug Impurities/Metabolites;
Applications : Tamsulosin hydrochloride is a medication primarily used to treat symptoms of benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges and causes urinary problems in men. It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. Tamsulosin is classified as an alpha-1 adrenergic blocker. While it's mainly prescribed for BPH, Tamsulosin can also be used off-label to treat kidney stones, as it helps relax the muscles in the urinary tract, which may assist in the passage of the stones.
Storage : <15°C Dark Place
Packing : 25kg/drum with double plastic bags inside; packed in a cardboard drum or fibre HDPE drum.
Storage : Stored in a clean, cool, dry area; keep away from moisture and direct from light/heat
Self-Life : 5 years if sealed and store away from direct sun light at 4-8°C
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