Product Details

Specifications

Chemical Name : Tofacitinib Citrate

CAS Number : 540737-29-9

Alternate CAS Number : 477600-75-2 (Free Base)

Synonyms : CP-690550, Tasocitinib, (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate salt, and Xeljanz

Molecular Formula : C22H28N6O8

Molecular Weight : 504.50 (312.38 + 192.12)

Appearance : White to Off-White Crystalline Solid

Melting Point : 200-202°C

Solubility : Water, Methanol, Acetone(Slightly), DMSO(Slightly)

Category : Pharmaceutical/Standards/API Drug Impurities/Metabolites;

Applications : Tofacitinib citrate API is used primarily to treat moderate to severe cases of rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and polyarticular course juvenile idiopathic arthritis (pcJIA) as it acts as a Janus kinase (JAK) inhibitor, helping to suppress the immune system and reduce inflammation in these conditions; it can be administered alone or in combination with other medications depending on the patient's needs.

Storage : 20-25°C

Packaging Details

Packing : 25kg/drum with double plastic bags inside; packed in a cardboard drum or fibre HDPE drum.
Storage : Stored in a clean, cool, dry area; keep away from moisture and direct from light/heat
Self-Life : 5 years if sealed and store away from direct sun light at 4-8°C